Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691199 | 1.00 | KCNA3 (0.62) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL5396825 | 0.87 | NQO1 (0.67) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL13769007 | 0.85 | LMNA (0.59) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL30228452 | 0.85 | ALDH1A1 (0.59) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL30228337 | 0.83 | CA12 (0.65) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL22431749 | 0.83 | CA12 (0.70) | KCNA3ALDH1A1LMNAMAOACA12 | |
| SCHEMBL30227952 | 0.83 | KCNA3 (0.59) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL30228248 | 0.83 | CA12 (0.70) | KCNA3ALDH1A1LMNAMAOACA12 | |
| SCHEMBL31089772 | 0.83 | ALDH1A1 (0.50) | KCNA3ALDH1A1LMNASMN1; SMN2MAOA | |
| SCHEMBL30231784 | 0.81 | KDM4E (0.67) | KCNA3ALDH1A1LMNAMAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |