Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396825 | 0.87 | NQO1 (0.67) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL11476090 | 0.85 | CA12 (0.68) | CA12CA9ALDH1A1KDM4EHPGD | |
| SCHEMBL20154078 | 0.83 | CA12 (0.50) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL14424514 | 0.81 | NQO1 (0.47) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28227416 | 0.79 | CA12 (0.70) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL5691199 | 0.79 | KCNA3 (0.62) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28143420 | 0.79 | CA12 (0.66) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL30228412 | 0.79 | KCNA3 (0.62) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28053827 | 0.79 | NQO1 (0.53) | NQO1CA12CA9CA1ALDH1A1 | |
| SCHEMBL28843363 | 0.79 | KDM4E (0.62) | NQO1CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812473-A | Naphthyl-coumarin molecular probe and synthetic method and application thereof | 达州中医药职业学院 | 2024-10-22 | — | — | CN | disclosed |
| US-7259265-B2 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-21 | — | — | US | disclosed |
| US-7259265-B2 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-21 | — | — | US | disclosed |
| US-20060063806-A1 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMESTRY CHINESE ACADEMY OF SCIENCE (CN) | 2006-03-23 | — | — | US | disclosed |
| EP-1634878-A1 | COUMARINS COMPOUNDS, THE PREPARATION AND THE USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2006-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063806-A1 | Coumarin compounds and method for preparing and using the same | CBR3, AOC3, AOC2 | NQO1 147/4885CA12 1628/4885CA9 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.