Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13310389 | 0.87 | LTA4H (0.50) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL12805390 | 0.86 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL29459449 | 0.85 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1CNR1 | |
| SCHEMBL50818 | 0.85 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1CNR1 | |
| SCHEMBL5911145 | 0.83 | ESR1 (0.64) | ESR1ESR2CYP3A4ALDH1A1CNR1 | |
| SCHEMBL24437034 | 0.83 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| Phenol SCHEMBL4313239 | 0.81 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1CNR1 | |
| SCHEMBL450261 | 0.81 | LTA4H (0.62) | CYP3A4ALDH1A1LTA4HNR1H2BAX | |
| SCHEMBL28248699 | 0.80 | SMN1; SMN2 (0.49) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL10492973 | 0.79 | ESR1 (0.76) | ESR1ESR2CYP3A4ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492531-A | Dark polycarbonate composition | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-13 | — | — | CN | disclosed |