Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.39 |
| ▸ | KDM5C | P41229 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27421017 | 1.00 | TSHR (0.43) | TSHREGLN1LMNAALKBH5SUCNR1 | |
| Adipic Acid SCHEMBL27649162 | 0.91 | TSHR (0.50) | TSHRLMNAALDH1A1HSD17B10ABCC4 | |
| Acrylic Acid Methyl Ester SCHEMBL27374430 | 0.89 | FFAR3 (0.54) | TSHRHCAR2KEAP1NFE2L2HPGD | |
| Succinic Acid SCHEMBL27504197 | 0.88 | ALDH1A1 (0.48) | TSHREGLN1LMNAALKBH5SUCNR1 | |
| Malonic Acid SCHEMBL7939336 | 0.88 | LDHA (0.45) | TSHRLMNAHCAR2KEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL2957775 | 0.87 | — | — | |
| Pimelic Acid SCHEMBL28853927 | 0.87 | ALDH1A1 (0.50) | TSHRLMNAALDH1A1HSD17B10ABCC4 | |
| Acrylic Acid Methyl Ester SCHEMBL14892886 | 0.87 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL28304536 | 0.86 | HCAR2 (0.42) | TSHREGLN1LMNAHCAR2KEAP1 | |
| Acrylic Acid Methyl Ester SCHEMBL27557604 | 0.86 | FFAR3 (0.48) | TSHRLMNAHCAR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114702-A | Colour filter color material dispersion liquid, colour filter colored resin composition, colour filter and display equipment | DNP精细化工股份有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-105378615-B | The manufacturing method of touch panel negative-type photosensitive white composition, touch panel and touch panel | 东丽株式会社 | 2019-05-31 | — | — | CN | disclosed |
| CN-109415572-A | Color material dispersion liquid, colored resin composition, colour filter, liquid crystal display and light-emitting display apparatus | 大日本印刷株式会社 | 2019-03-01 | — | — | CN | disclosed |
| CN-108700686-A | Colored resin composition for color filter, pigment dispersion liquid, color filter, and display device | DNP精细化工股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-105934450-B | Curable composition | 株式会社LG化学 | 2018-06-08 | — | — | CN | disclosed |
| CN-107107542-A | Laminated substrate, glass cover-plate, the manufacture method of contact panel and laminated substrate | 东丽株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-105143354-B | Color material, color material dispersion liquid, colored filter colored resin composition, colored filter, liquid crystal indicator and organic light-emitting display device | 大日本印刷株式会社 | 2016-11-30 | — | — | CN | disclosed |
| CN-103650107-B | Impressing solidification compound, patterning method and pattern | 富士胶片株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-105934450-A | Curable composition | 株式会社LG化学 | 2016-09-07 | — | — | CN | disclosed |
| CN-104246548-B | Colored filter color material dispersion liquid, colored filter colored resin composition, colored filter and liquid crystal indicator and organic light-emitting display device | 大日本印刷株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-105794331-A | Electronic element and sheet material | 东洋油墨SC控股株式会社 | 2016-07-20 | — | — | CN | disclosed |
| CN-105765009-A | Photocurable inkjet ink | 捷恩智株式会社 | 2016-07-13 | — | — | CN | disclosed |
| CN-105765011-A | Photocurable inkjet ink | 捷恩智株式会社 | 2016-07-13 | — | — | CN | disclosed |
| CN-105378615-A | Negative-type photosensitive white composition for touch panel, touch panel, and production method for touch panel | TORAY INDUSTRIES | 2016-03-02 | — | — | CN | disclosed |
| CN-102652283-A | Novel compound, pigment dispersion composition and photosensitive resin composition including the same, and color filter using the same | CHEIL IND INC | 2012-08-29 | — | — | CN | disclosed |