Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20330054 | 0.95 | ABCB1 (0.49) | MMP1MAOBABCB1LMNAALDH1A1 | |
| SCHEMBL10382406 | 0.88 | KMT2A (0.51) | MMP12ALDH1A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL27884801 | 0.86 | ABCB1 (0.45) | MMP1MAOBABCB1LMNAALDH1A1 | |
| SCHEMBL27910542 | 0.85 | ALDH1A1 (0.46) | LMNAALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6154183 | 0.82 | ABCB1 (0.48) | MAOBABCB1MMP12ALDH1A1KMT2A | |
| SCHEMBL6154182 | 0.82 | ABCB1 (0.48) | MAOBABCB1MMP12ALDH1A1KMT2A | |
| SCHEMBL21367029 | 0.82 | ABCB1 (0.43) | MMP1MAOBABCB1LMNAALDH1A1 | |
| SCHEMBL28790050 | 0.82 | SLC1A3 (0.46) | MMP12ALDH1A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL12136516 | 0.82 | SLC1A3 (0.46) | MMP12ALDH1A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL24335280 | 0.81 | MMP1 (0.48) | MMP1MAOBABCB1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105385714-A | Method for preparing rosuvastatin intermediate through biological enzyme with chemical method | SYNCOZYMES (SHANGHAI) CO LTD | 2016-03-09 | — | — | CN | disclosed |