Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256120 | 0.85 | NPSR1 (0.37) | SLC6A2SLC6A4MEN1LMNACYP2D6 | |
| SCHEMBL3837450 | 0.79 | SLC6A2 (0.62) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL3544485 | 0.79 | SLC18A3 (0.48) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL18263847 | 0.78 | SLC6A2 (0.60) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL4010135 | 0.76 | SLC18A3 (0.45) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL22634123 | 0.76 | SLC18A3 (0.45) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL4389599 | 0.74 | SLC6A2 (0.44) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL18270999 | 0.74 | SLC6A4 (0.57) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL6738802 | 0.73 | SLC18A3 (0.42) | SLC18A3SIGMAR1SLC6A2SLC6A4HRH1 | |
| SCHEMBL18271346 | 0.73 | SLC6A2 (0.56) | SLC6A2SLC6A4HRH1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570630-B | Nitrogen heterocyclic derivative and the application in medicine thereof | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |