SCHEMBL6738802

SCHEMBL6738802

c1ccc(N(C2CCCNCC2)C2CCCNCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
SLC6A4 P31645 8/20 0.42
SLC6A2 P23975 7/20 0.42
SLC6A3 Q01959 3/20 0.42
HRH1 P35367 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
SCN1A P35498 1/20 0.41
KMT2A Q03164 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
GBA1 P04062 1/20 0.39
KCNH2 Q12809 1/20 0.39
NOS2 P35228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3544485 0.92 SLC18A3 (0.48) SLC18A3SIGMAR1SLC6A4SLC6A2SLC6A3
SCHEMBL4965358 0.82 HRH1 (0.42) SLC18A3SIGMAR1SLC6A4SLC6A2SLC6A3
SCHEMBL28581310 0.82 KDM4E (0.46) MEN1LMNAKMT2A
SCHEMBL620016 0.80 KDM4E (0.49) MEN1LMNAKMT2A
SCHEMBL24537399 0.78 KDM4E (0.47) MEN1LMNAKMT2A
SCHEMBL17046065 0.78 KDM4E (0.47) MEN1LMNAKMT2A
Hydrochloric Acid SCHEMBL2140316 0.78 KDM4E (0.47) MEN1LMNAKMT2A
SCHEMBL2346417 0.77 TAAR1 (0.42) SLC6A4SLC6A2SLC6A3HRH1MEN1
SCHEMBL3837450 0.76 SLC6A2 (0.62) SLC18A3SIGMAR1SLC6A4SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL18263847 0.75 SLC6A2 (0.60) SLC18A3SIGMAR1SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004111062-A1 PARA-PHENYLENEDIAMINE DERIVATIVES COMPRISING A DIAZACYCLOHEPTANE RING SUBSTITUTED WITH A SILYL RADICAL, FOR DYEING KERATIN FIBRES L'OREAL (FR) 2004-12-23 WO claimed