Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054262 | 1.00 | ALOX15 (0.41) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL224633 | 0.83 | ALOX15 (0.52) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL7603527 | 0.79 | ALOX15 (0.46) | ALOX15TSHRLMNACYP1A2SMN1; SMN2 | |
| SCHEMBL28054251 | 0.78 | ALOX15 (0.38) | ALOX15TSHRLMNACYP1A2SMN1; SMN2 | |
| SCHEMBL22286874 | 0.78 | ALOX15 (0.46) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL28880337 | 0.78 | ALOX15 (0.46) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL27667534 | 0.78 | ALOX15 (0.46) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL24733682 | 0.76 | CYP3A4 (0.50) | ALOX15TSHRCYP3A4ATMTDP1 | |
| Iodide SCHEMBL872505 | 0.74 | CYP3A4 (0.49) | ALOX15TSHRCYP3A4ATMTDP1 | |
| SCHEMBL10581042 | 0.74 | TSHR (0.44) | ALOX15TSHRCYP3A4ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102884053-B | Cyclopropanecarboxylic acid derivatives | DAIICHI SANKYO Co.,Ltd. (JP) | 2016-03-02 | — | — | CN | disclosed |