Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224633 | 0.89 | ALOX15 (0.52) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL1931920 | 0.84 | ALDH1A1 (0.60) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL27667534 | 0.83 | ALOX15 (0.46) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL22286874 | 0.83 | ALOX15 (0.46) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL24733682 | 0.81 | CYP3A4 (0.50) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL31500212 | 0.80 | CYP1A2 (0.38) | ALOX15TSHRCYP1A2SMN1; SMN2CYP2D6 | |
| Iodide SCHEMBL872505 | 0.79 | CYP3A4 (0.49) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL10581042 | 0.79 | TSHR (0.44) | ALOX15TSHRTDP1CYP3A4ATM | |
| SCHEMBL17660910 | 0.79 | TSHR (0.44) | TSHRTDP1CYP3A4ATMCYP1A2 | |
| SCHEMBL467542 | 0.78 | CYP3A4 (0.66) | TSHRTDP1CYP3A4ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078725-B | Compound for targeted ubiquitination degradation of GSK-3 beta protein and application thereof | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |