Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724169 | 1.00 | GAA (0.41) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL193889 | 0.87 | CYP11B1 (0.40) | SMN1; SMN2CYP11B1CYP11B2HTR6SLC22A12 | |
| SCHEMBL29815691 | 0.87 | CYP11B1 (0.40) | SMN1; SMN2CYP11B1CYP11B2HTR6SLC22A12 | |
| SCHEMBL28857181 | 0.85 | CYP11B1 (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29601512 | 0.85 | CYP11B1 (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28221109 | 0.84 | HTR6 (0.36) | KDM4ECYP11B1CYP11B2HTR6SLC22A12 | |
| SCHEMBL31647759 | 0.84 | CHRNB2 (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL20784007 | 0.84 | CHRNB2 (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28227721 | 0.83 | CHRNB2 (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL30903548 | 0.82 | CHRNB2 (0.38) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853728-B | Vonopraz fumarate tablet and preparation method thereof | 四川制药制剂有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-114853728-A | Vonola fumarate tablet and preparation method thereof | 四川制药制剂有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-108503621-B | Preparation method of vonoprazan fumarate | 上海中拓医药科技有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-108503621-A | A kind of preparation method of Vonoprazan fumarate | 上海中拓医药科技有限公司 | 2018-09-07 | — | — | CN | claimed |
| CN-117466867-A | Novel process for synthesizing voronoi and application thereof | 苏州健雄职业技术学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-114853728-B | Vonopraz fumarate tablet and preparation method thereof | 四川制药制剂有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116082305-A | Preparation method and application of voronoi free base | 佛山奕安赛医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114853728-A | Vonola fumarate tablet and preparation method thereof | 四川制药制剂有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-108503621-B | Preparation method of vonoprazan fumarate | 上海中拓医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-108503621-B | Preparation method of vonoprazan fumarate | 上海中拓医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-108503621-A | A kind of preparation method of Vonoprazan fumarate | 上海中拓医药科技有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-104860923-B | The preparation method of Vonoprazan fumarate | 山东康美乐医药科技有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-105503828-A | Preparation method of fumarate of pyrrole derivatives | BEIJING KANG LISHENG PHARMACEUTICAL TECH DEV CO LTD | 2016-04-20 | — | — | CN | disclosed |