Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675903 | 0.95 | ALOX5 (0.49) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL19102189 | 0.93 | ALOX5 (0.47) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL19303145 | 0.93 | ALOX5 (0.47) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL12093550 | 0.89 | SLC13A5 (0.51) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL23251406 | 0.86 | SLC13A5 (0.51) | SLC13A5L3MBTL1MEN1KMT2ACYP3A4 | |
| SCHEMBL31561751 | 0.86 | SLC13A5 (0.49) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL27939661 | 0.84 | SLC13A5 (0.48) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL12134746 | 0.84 | SLC13A5 (0.41) | SLC13A5ALOX5PTGS2TDP1L3MBTL1 | |
| SCHEMBL29138536 | 0.84 | SLC13A5 (0.51) | SLC13A5HTR2AHTR2CKDM1AMAOA | |
| SCHEMBL8234951 | 0.83 | SLC13A5 (0.47) | SLC13A5HTR2AHTR2CKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330595-A | Pyridine derivative and application thereof to mycobacterium resistance | NANJING MINGDE DRUG R & D CO LTD | 2016-02-17 | — | — | CN | disclosed |