SCHEMBL675903

SCHEMBL675903

CCCCCc1cccnc1OC

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
PTGS2 P35354 1/20 0.49
SLC13A5 Q86YT5 3/20 0.48
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PPARA Q07869 1/20 0.43
LIPG Q9Y5X9 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
KDM1A O60341 5/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 1/20 0.42
APLNR P35414 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19303145 0.98 ALOX5 (0.47) ALOX5PTGS2SLC13A5TDP1L3MBTL1
SCHEMBL19102189 0.98 ALOX5 (0.47) ALOX5PTGS2SLC13A5TDP1L3MBTL1
SCHEMBL28054534 0.95 SLC13A5 (0.49) ALOX5PTGS2SLC13A5TDP1L3MBTL1
SCHEMBL12093550 0.87 SLC13A5 (0.51) SLC13A5HTR2AHTR2CKDM1AMAOA
SCHEMBL8234951 0.85 SLC13A5 (0.47) ALOX5PTGS2SLC13A5HTR2AHTR2C
SCHEMBL31561751 0.84 SLC13A5 (0.49) SLC13A5HTR2AHTR2CKDM1AMAOA
SCHEMBL27939661 0.83 SLC13A5 (0.48) SLC13A5HTR2AHTR2CKDM1AMAOA
SCHEMBL29138536 0.83 SLC13A5 (0.51) SLC13A5L3MBTL1HTR2AHTR2CKDM1A
SCHEMBL23251406 0.81 SLC13A5 (0.51) SLC13A5L3MBTL1
SCHEMBL16057097 0.80 THRA (0.47) SLC13A5PPARALIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150190504-A1 WOUND HEALING KINETIC CONCEPTS, INC. 2015-07-09 US disclosed
US-8957076-B2 Wound healing SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2015-02-17 US disclosed
US-8063052-B2 Wound healing SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2011-11-22 US disclosed
US-20100099622-A1 WOUND HEALING SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2010-04-22 US disclosed
US-20090170910-A1 WOUND HEALING KCI USA, INC. 2009-07-02 US disclosed
EP-1786409-A1 WOUND HEALING ETHICON, INC. (US) 2007-05-23 EP disclosed
WO-2006028836-A1 WOUND HEALING ETHICON, INC. (US) 2006-03-16 WO disclosed
CN-1316995-A Hydroxy 2-piperidinoate hydroxamic acid derivatives as MMP inhibitors PFIZER PROD INC (US) 2001-10-10 CN disclosed
CN-1039183-C 2, 6-substituted pyridine herbicides SHELL INT RESEARCH (NL) 1998-07-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099622-A1 WOUND HEALING MAPK1, MAPK3, MAPK4 ALOX5 1093/4885PTGS2 117/4885SLC13A5 4159/4885
US-20090170910-A1 WOUND HEALING MAPK1, MAPK3, MAPK4 ALOX5 1093/4885PTGS2 117/4885SLC13A5 4159/4885
US-20150190504-A1 WOUND HEALING MAPK1, MAPK3, MAPK4 ALOX5 1093/4885PTGS2 117/4885SLC13A5 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.