Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054501 | 0.81 | MAPT (0.51) | ALDH1A1TSHRCYP3A4MAPTNPC1 | |
| SCHEMBL27895051 | 0.78 | MAPT (0.55) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL28054505 | 0.78 | PTPN1 (0.46) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL28054607 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP3A4MAPTNPC1 | |
| SCHEMBL7190826 | 0.76 | TSHR (0.64) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL17117159 | 0.74 | TSHR (0.62) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL7236715 | 0.71 | MAPT (0.52) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL12643379 | 0.71 | MAPT (0.69) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL1226499 | 0.71 | NPC1 (0.49) | ALDH1A1TSHRRECQLCYP3A4MAPT | |
| SCHEMBL27742209 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRRECQLCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669564-A | Urea compound and preparation method, medicine composition, intermediate and application thereof | 上海医药工业研究院 | 2016-06-15 | — | — | CN | disclosed |
| CN-102958921-B | Urea compound, preparation method thereof, intermediate thereof and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-03-23 | — | — | CN | disclosed |