Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117159 | 0.98 | TSHR (0.62) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL9999827 | 0.92 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL1514401 | 0.90 | CRHBP (0.58) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL15203036 | 0.90 | CRHBP (0.58) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL20364812 | 0.89 | ALDH1A1 (0.53) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL31436939 | 0.89 | ALDH1A1 (0.53) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL1896442 | 0.89 | ALDH1A1 (0.53) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL3537270 | 0.87 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL10475465 | 0.87 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4RECQLMAPT | |
| SCHEMBL9807408 | 0.87 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |
| JP-4368364-A | — | — | None | — | — | JP | disclosed |
| US-9499555-B2 | Porous crystalline frameworks, process for the preparation therof and their mechanical delamination to covalent organic nanosheets (CONS) | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-11-22 | — | — | US | disclosed |
| US-20150266885-A1 | POROUS CRYSTALLINE FRAMEWORKS, PROCESS FOR THE PREPARATION THEROF AND THEIR MECHANICAL DELAMINATION TO COVALENT ORGANIC NANOSHEETS (CONS) | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-09-24 | — | — | US | disclosed |
| US-8962670-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8962670-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8637490-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637490-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20130045949-A1 | ANTI-CANCER AGENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20130045949-A1 | ANTI-CANCER AGENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20110268472-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110268472-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | US | disclosed |
| US-7850868-B2 | Lyotropic liquid crystalline mixture, coating liquid, and optical anisotropic film | NITTO DENKO CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-7850868-B2 | Lyotropic liquid crystalline mixture, coating liquid, and optical anisotropic film | NITTO DENKO CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20100038589-A1 | LYOTROPIC LIQUID CRYSTALLINE MIXTURE, COATING LIQUID, AND OPTICAL ANISOTROPIC FILM | NITTO DENKO CORPORATION (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100038589-A1 | LYOTROPIC LIQUID CRYSTALLINE MIXTURE, COATING LIQUID, AND OPTICAL ANISOTROPIC FILM | NITTO DENKO CORPORATION (JP) | 2010-02-18 | — | — | US | disclosed |
| JP-H04368364-A | PRODUCTION OF 4-METHYL-3-NITROBENZENESULFONIC ACID | NISSAN CHEM IND LTD | 1992-12-21 | — | — | JP | disclosed |
| US-3950434-A | OXYGEN, PALLADIUM CATALYST, SULFURIC ACID | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266885-A1 | POROUS CRYSTALLINE FRAMEWORKS, PROCESS FOR THE PREPARATION THEROF AND THEIR MECHANICAL DELAMINATION TO COVALENT ORGANIC NANOSHEETS (CONS) | CTSF, DCAF1, POF1B | TSHR 3471/4885ALDH1A1 4461/4885CYP3A4 2298/4885 |
| US-20130045949-A1 | ANTI-CANCER AGENTS | TP53, MCL1, HRAS | TSHR 4523/4885ALDH1A1 740/4885CYP3A4 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.