SCHEMBL28054579

SCHEMBL28054579

C=CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.OCC(CO)(CO)CO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.54
TSHR P16473 4/20 0.54
MAPK1 P28482 3/20 0.54
LMNA P02545 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
MEN1 O00255 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
BLM P54132 2/20 0.54
KMT2A Q03164 2/20 0.54
ATM Q13315 2/20 0.54
HIF1A Q16665 2/20 0.54
GMNN O75496 1/20 0.54
GABBR2 O75899 1/20 0.54
TP53 P04637 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
CYP2C19 P33261 1/20 0.54
PMP22 Q01453 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463408 0.93 ALDH1A1 (0.53) ALDH1A1TSHRMAPK1LMNANPSR1
1,6-Hexanediol SCHEMBL28904411 0.87 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL28179323 0.86 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL1598616 0.83 HSPA5 (0.53) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL11318043 0.82 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1LMNANPSR1
Propionic Acid SCHEMBL17825585 0.82 GAA (0.48) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL463139 0.81 HSPA5 (0.65) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL26328615 0.80 HSPA5 (0.58) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL27683623 0.79 HSPA5 (0.49) ALDH1A1TSHRMAPK1LMNANPSR1
SCHEMBL11307397 0.78 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103980686-B A kind of biodegradable packaging tube material of germ resistance and flexible pipe preparation method thereof CHENGYI PLASTIC PRODUCTS CO., LTD., SHANGHAI (CN) 2016-03-23 CN claimed