SCHEMBL463139

SCHEMBL463139

C=CCc1cc(Cc2cc(CC=C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.65
HIF1A Q16665 4/20 0.53
CYP2C9 P11712 3/20 0.53
CYP2C19 P33261 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CYP2D6 P10635 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 5/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
BLM P54132 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 2/20 0.42
MAPT P10636 2/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1598616 0.92 HSPA5 (0.53) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
Acrylic Acid SCHEMBL11068068 0.91 HSPA5 (0.55) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL26328615 0.89 HSPA5 (0.58) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL463408 0.88 ALDH1A1 (0.53) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL27683623 0.87 HSPA5 (0.49) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL14588188 0.85 HSPA5 (0.67) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL11068059 0.83 HSPA5 (0.47) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL28179323 0.81 ALDH1A1 (0.52) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL10492380 0.81 HSPA5 (0.41) HSPA5ALDH1A1NPSR1MEN1CYP3A4
SCHEMBL28054579 0.81 ALDH1A1 (0.54) HSPA5HIF1ACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11162048-B2 Lubricating composition with alkylated naphthylamine THE LUBRIZOL CORPORATION (US) 2021-11-02 US claimed
EP-3562922-B1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE LUBRIZOL CORP (US) 2021-02-03 EP claimed
EP-3562922-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE The Lubrizol Corporation (US) 2019-11-06 EP claimed
US-20190316056-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE THE LUBRIZOL CORPORATION (US) 2019-10-17 US claimed
WO-2018125567-A1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE THE LUBRIZOL CORPORATION (US) 2018-07-05 WO claimed
JP-61241347-A None JP disclosed
JP-59071341-A None JP disclosed
JP-7324153-A None JP disclosed
JP-61258856-A None JP disclosed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-4732923-A UNSATURATED PHENOLIC STABILIZERS SUMITOMO CHEMICAL CO., LTD. (JP) 1988-03-22 US disclosed
EP-0117328-B1 LIQUID FUELS CONTAINING CORROSION INHIBITORS, AND INHIBITOR CONCENTRATES ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1987-04-29 EP disclosed
EP-0210046-A2 Thermally resistant butadiene polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-28 EP disclosed
JP-S61258856-A LOW-TEMPERATURE IMPACT-RESISTANT RESIN COMPOSITION HAVING IMPROVED COLORING PROPERTY AND THERMAL DECOMPOSITION RESISTANCE SUMITOMO NAUGATUCK CO LTD 1986-11-17 JP disclosed
JP-S61241347-A RESIN COMPOSITION HAVING IMPROVED COLORING PROPERTY AND RESISTANCE TO THERMAL DECOMPOSITION SUMITOMO NAUGATUCK CO LTD 1986-10-27 JP disclosed
US-4525514-A A PENTAERYTHRICTOL TETRAKIS/ALKYLTHIO PROPIONATE/ AND A PHENOL-CONTAINING CARBOACRYLATE; SYNTHETIC RUBBERS SUMITOMO CHEMICAL CO., LTD. (JP) 1985-06-25 US disclosed
JP-S5971341-A STABILIZER FOR SYNTHETIC RESIN SUMITOMO CHEM CO LTD 1984-04-23 JP disclosed
JP-S05971341-A 0001-01-01 JP disclosed