Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17976212 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1KDM4ECHRM2HDAC6 | |
| SCHEMBL19222207 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CHRM2HDAC6LMNA | |
| SCHEMBL28205756 | 0.74 | KCNN4 (0.36) | SMN1; SMN2KDM4EHDAC6LMNAALDH1A1 | |
| SCHEMBL21742092 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1KDM4ECHRM2HDAC6 | |
| SCHEMBL11022686 | 0.72 | CLK4 (0.42) | HDAC6GAAKMT2A | |
| SCHEMBL21742276 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM2HDAC6LMNA | |
| SCHEMBL21742075 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM2HDAC6LMNA | |
| SCHEMBL6541865 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL14395280 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1KDM4ECHRM2HDAC6 | |
| SCHEMBL21742196 | 0.70 | CHRM2 (0.44) | SMN1; SMN2L3MBTL1NPC1RAB9ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392777-A | Biaryl derivatives as GRP120 agonists | LG LIFE SCIENCES LTD | 2016-03-09 | — | — | CN | disclosed |