Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019919 | 0.88 | CLK4 (0.30) | CLK4 | |
| SCHEMBL11024100 | 0.82 | KIF11 (0.38) | MAPT | |
| SCHEMBL11026542 | 0.81 | NPC1 (0.35) | GAAMAPTKMT2A | |
| SCHEMBL11020353 | 0.80 | LMNA (0.36) | MAPTPOLBKMT2A | |
| SCHEMBL11022655 | 0.79 | EDNRB (0.39) | GAAPOLB | |
| SCHEMBL28205756 | 0.78 | KCNN4 (0.36) | POLBKMT2AHDAC6 | |
| SCHEMBL11197778 | 0.77 | CYP2A6 (0.41) | GAAMAPTKMT2AHDAC6CYP2A6 | |
| SCHEMBL2574861 | 0.75 | ESR1 (0.44) | — | |
| SCHEMBL28149485 | 0.75 | LMNA (0.33) | GAAMAPTPOLBKMT2A | |
| SCHEMBL4689119 | 0.74 | MEN1 (0.46) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031796-B1 | 4-HETEROCYCLYL-4'-VINYL-STILBENES | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0020298-B1 | BENZOXAZOLYL STILBENES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS FOR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4297234-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0031796-A2 | 4-Heterocyclyl-4'-vinyl-stilbenes | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| EP-0020298-A1 | Benzoxazolyl stilbenes, process for their preparation and their use as optical brighteners for organic materials | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |