Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496121 | 0.92 | MCHR1 (0.44) | NOS1NOS3 | |
| SCHEMBL2144739 | 0.88 | MCHR1 (0.43) | NOS1NOS3 | |
| SCHEMBL8210420 | 0.86 | NOS1 (0.40) | NOS1NOS3 | |
| SCHEMBL2144370 | 0.85 | NOS1 (0.40) | NOS1NOS3APPBACE1 | |
| SCHEMBL2143997 | 0.81 | MCHR1 (0.50) | NOS1NOS3 | |
| SCHEMBL8209632 | 0.81 | NOS1 (0.48) | NOS1NOS3 | |
| SCHEMBL14000807 | 0.81 | NOS1 (0.48) | NOS1NOS3 | |
| SCHEMBL24068592 | 0.77 | AURKA (0.44) | — | |
| SCHEMBL22606727 | 0.77 | FFAR4 (0.41) | — | |
| SCHEMBL3926302 | 0.77 | ADORA2A (0.43) | NOS1NOS3APPBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-105392777-A | Biaryl derivatives as GRP120 agonists | LG LIFE SCIENCES LTD | 2016-03-09 | — | — | CN | disclosed |