Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054787 | 0.91 | MEN1 (0.61) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054775 | 0.91 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054783 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28826405 | 0.90 | TSHR (0.56) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054781 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054777 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054797 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054795 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTNPSR1LMNA | |
| SCHEMBL28054691 | 0.81 | ACHE (0.53) | ALDH1A1TSHRMAPTLMNAHPGD | |
| SCHEMBL14407560 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693681-A | Trifluoromethyl chromene derivative and synthetic method thereof | 上海大学 | 2016-06-22 | — | — | CN | disclosed |