SCHEMBL28055090

SCHEMBL28055090

CC1=Cc2ccccc2C1c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.39
MAOB P27338 2/20 0.39
MAOA P21397 1/20 0.36
TAAR1 Q96RJ0 2/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
EPHX1 P07099 1/20 0.34
HTR2C P28335 1/20 0.33
IDO1 P14902 1/20 0.32
AGXT P21549 1/20 0.32
ALDH1A1 P00352 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673270 0.89 GAA (0.35) CYP3A4MEN1KMT2AIDO1
SCHEMBL5080422 0.82 MEN1 (0.34) MEN1KMT2A
SCHEMBL4006148 0.81 MEN1 (0.33) MEN1KMT2A
SCHEMBL27910138 0.79 TSHR (0.41) KDM1ATDP1MEN1KMT2AALDH1A1
SCHEMBL27475455 0.77 BRD4 (0.36) HSD17B10TDP1ALDH1A1EDNRBEDNRA
SCHEMBL6662143 0.76 CYP2A6 (0.38) CYP3A4HSD17B10TDP1HTR2CALDH1A1
SCHEMBL28237677 0.76 KDM1A (0.34) KDM1AMAOBTAAR1HSD17B10EPHX1
SCHEMBL28055117 0.75 RAB9A (0.41) KDM1AMAOBTAAR1CYP3A4HSD17B10
SCHEMBL23088743 0.75 ADRA2C (0.32) CYP3A4MEN1KMT2A
SCHEMBL30525101 0.75 ADRA2C (0.32) CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377905-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-09-14 CN disclosed
CN-105377904-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-07-10 CN disclosed
CN-105377904-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed