Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154678 | 0.87 | PELI1 (0.44) | PELI1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL8154684 | 0.87 | PELI1 (0.44) | PELI1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL6010547 | 0.85 | KDM4E (0.64) | KDM4EHSD17B10MAPTMEN1ALDH1A1 | |
| SCHEMBL8916399 | 0.79 | KDM4E (0.69) | PELI1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL1314851 | 0.79 | KDM4E (0.69) | PELI1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL29773361 | 0.79 | KDM4E (0.69) | PELI1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL6029975 | 0.76 | P4HB (0.44) | PELI1APPPOLBCYP2C9CYP1A2 | |
| SCHEMBL3890018 | 0.76 | P4HB (0.44) | PELI1APPPOLBCYP2C9CYP1A2 | |
| SCHEMBL5682708 | 0.75 | KDM4E (0.57) | KDM4EHSD17B10MAPTMEN1ALDH1A1 | |
| SCHEMBL28662307 | 0.75 | APP (0.71) | KDM4EHSD17B10MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264693-B | The acrylamide derivative of inhibitor is changed as mitochondrial permeability | CONGENIA S.R.L. (IT) | 2016-01-27 | — | — | CN | disclosed |