SCHEMBL8916399

SCHEMBL8916399

NC(=O)/C=C/c1ccc(O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.69
MAPT P10636 3/20 0.69
TTR P02766 3/20 0.69
KMT2A Q03164 3/20 0.69
HSD17B10 Q99714 2/20 0.69
APP P05067 2/20 0.69
GAA P10253 2/20 0.69
PTPN1 P18031 2/20 0.69
MAPK1 P28482 2/20 0.69
MEN1 O00255 2/20 0.69
AKR1B1 P15121 2/20 0.69
NFKB1 P19838 2/20 0.69
DPP4 P27487 2/20 0.69
HDAC6 Q9UBN7 2/20 0.69
HDAC3 O15379 1/20 0.69
CA12 O43570 1/20 0.69
AKR1B10 O60218 1/20 0.69
ALDH1A1 P00352 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1314851 1.00 KDM4E (0.69) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL29773361 1.00 KDM4E (0.69) KDM4EMAPTTTRKMT2AHSD17B10
Phenol SCHEMBL28949254 0.90 MMP1 (0.62) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL2221673 0.83 KDM4E (0.74) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL5598948 0.83 KDM4E (0.74) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL30740005 0.83 PELI1 (0.53) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL30739974 0.83 PELI1 (0.53) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL21986709 0.83 PELI1 (0.53) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL30740008 0.83 PELI1 (0.53) KDM4EMAPTTTRKMT2AHSD17B10
SCHEMBL21986714 0.83 PELI1 (0.53) KDM4EMAPTTTRKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228667-A1 METHODS FOR REVERSING HEPATIC STEATOSIS Brightseed, Inc. (US) 2023-08-23 EP claimed
EP-4003060-A1 METHOD FOR IMPROVING DIGESTIVE HEALTH Brightseed, Inc. (US) 2022-06-01 EP claimed
WO-2022081567-A1 METHODS FOR REVERSING HEPATIC STEATOSIS BRIGHTSEED, INC. (US) 2022-04-21 WO claimed
JP-2104568-A None JP disclosed
US-20260102332-A1 Enhanced Toothpaste And Kits BEAUTYPASTE INC. (US) 2026-04-16 US disclosed
EP-4465976-A1 USES AND METHODS FOR PROMOTING INCREASED MITOCHONDRIAL MASS AND FUNCTION Brightseed, Inc. (US) 2024-11-27 EP disclosed
US-11801216-B2 Enhanced toothpaste and kits BEAUTYPASTE INC. (US) 2023-10-31 US disclosed
WO-2023141427-A1 USES AND METHODS FOR PROMOTING INCREASED MITOCHONDRIAL MASS AND FUNCTION BRIGHTSEED, INC. (US) 2023-07-27 WO disclosed
CN-115536604-A Caffeic acid amide compound and application thereof 广西大学 2022-12-30 CN disclosed
CN-115536604-A Caffeic acid amide compound and application thereof 广西大学 2022-12-30 CN disclosed
EP-4025181-A1 ENHANCED TOOTHPASTE AND KITS Beautypaste LLC (US) 2022-07-13 EP disclosed
US-8912332-B2 Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2014-12-16 US disclosed
EP-2428502-B1 Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces Justus Liebig Universität Giessen (DE) 2014-12-10 EP disclosed
US-20140357678-A1 COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) (AR) 2014-12-04 US disclosed
CN-103012181-B Method for compounding caffeoyl dopamine SUZHOU UUGENE BIOPHARMA CO LTD 2014-06-04 CN disclosed
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2013-09-19 US disclosed
CN-103012181-A Method for compounding caffeoyl dopamine SUZHOU UUGENE BIOPHARMA CO LTD 2013-04-03 CN disclosed
CN-1646480-A Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition MOGAM BIOTECH RES INST (KR) 2005-07-27 CN disclosed
US-5681708-A DISSOCIATE PROTEIN-PROTEIN COMPLEX SMITHKLINE BEECHAM CORPORATION (US) 1997-10-28 US disclosed
JP-H02104568-A ACTING AGENT OF PRODUCTION PROMOTION OF NERVE GROWTH FACTOR YOSHITOMI PHARMACEUT IND LTD 1990-04-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces CHRM3, CHRM5, CHRM4 KDM4E 1565/4885MAPT 4034/4885TTR 1485/4885
US-20260102332-A1 Enhanced Toothpaste And Kits TAS2R10, CENPE, TAS2R30 KDM4E 2025/4885MAPT 3718/4885TTR 2262/4885
US-20140357678-A1 COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM C5, CBR3, C1R KDM4E 2424/4885MAPT 4222/4885TTR 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.