SCHEMBL28055209

SCHEMBL28055209

C[SiH3].c1ccc([SiH2]c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ACHE P22303 2/20 0.44
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR3 P46089 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
TP53 P04637 1/20 0.32
CA4 P22748 1/20 0.32
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31
ESR2 Q92731 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52125 0.89 TSHR (0.44) TSHRACHELMNAALOX12HPGD
SCHEMBL28278745 0.89 TSHR (0.44) TSHRACHELMNAALOX12HPGD
Chloromethane SCHEMBL28762557 0.87 TSHR (0.44) TSHRACHELMNAALOX12HPGD
SCHEMBL27853772 0.87 TSHR (0.44) TSHRACHELMNAALOX12HPGD
SCHEMBL3133054 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD
Fluoride SCHEMBL704196 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD
Water SCHEMBL6913191 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD
Hydrochloric Acid SCHEMBL15122374 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD
Ammonia Solution, Strong SCHEMBL11868999 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD
Hydrochloric Acid SCHEMBL312008 0.86 TSHR (0.41) TSHRACHELMNAALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390656-A Method for continuously preparing ceramic matrix composite material section bar and section bar prepared by method 北京信汇碳硅科技有限公司 2021-02-23 CN claimed
CN-105385456-A Liquid crystal orientation agent, liquid crystal orientation film and manufacturing method thereof, liquid crystal display element, phase-difference film and manufacturing method thereof JSR CORP 2016-03-09 CN disclosed