Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.33 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5702857 | 1.00 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL15122374 | 1.00 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL28278745 | 0.96 | TSHR (0.44) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL52125 | 0.96 | TSHR (0.44) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL2793388 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11868999 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL2793385 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL28328350 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| Fluoride SCHEMBL704196 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 | |
| SCHEMBL3133054 | 0.92 | TSHR (0.41) | TSHRACHEALOX12LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053021-B1 | A POROUS ZEOLITE OF ORGANOSILICON, A METHOD FOR PREPARING THE SAME AND THE USE OF THE SAME | CHINA PETROLEUM & CHEMICAL (CN) | 2013-07-03 | — | — | EP | claimed |
| US-8030508-B2 | Porous zeolite of organosilicon, a method for preparing the same and the use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2011-10-04 | — | — | US | claimed |
| US-20090247776-A1 | POROUS ZEOLITE OF ORGANOSILICON, A METHOD FOR PREPARING THE SAME AND THE USE OF THE SAME | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2009-10-01 | — | — | US | claimed |
| EP-2053021-A1 | A POROUS ZEOLITE OF ORGANOSILICON, A METHOD FOR PREPARING THE SAME AND THE USE OF THE SAME | China Petroleum & Chemical Corporation (CN) | 2009-04-29 | — | — | EP | claimed |
| EP-3365379-B1 | PRODUCTION OF POLYOLEFINS WITH INTERNAL UNSATURATION STRUCTURES USING A METALLOCENE CATALYST SYSTEM | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-12-18 | — | — | EP | disclosed |
| EP-3717527-B1 | POLYETHYLENE COMPOSITIONS AND FILMS MADE THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-119143972-A | Blue heat-induced delayed fluorescent polymer and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-17 | — | — | CN | disclosed |
| US-11787881-B2 | Polyethylene compositions and films prepared therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-10-17 | — | — | US | disclosed |
| CN-111511781-B | Catalyst system and polymerization process using the same | 埃克森美孚化学专利公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-112218900-B | Catalyst system comprising two hafnocene catalyst compounds | 埃克森美孚化学专利公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-3717525-B1 | CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR USING THE SAME | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-112313254-B | Polyethylene compositions and films made therefrom | 埃克森美孚化学专利公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-1252815-A | Method for polymerizing alpha-olefins in a gaseous phase | BASF AG (DE) | 2000-05-10 | — | — | CN | disclosed |
| EP-0985685-A1 | CATALYSTS FOR OLEFIN POLYMER PRODUCTION AND PROCESS FOR PRODUCING OLEFIN POLYMER | Idemitsu Petrochemical Co., Ltd. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0945471-A1 | CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5919712-A | OPTICAL SUBSTRATE WITH SURFACE COATING FOR LINKING OF CAPTURE MOLECULE HAVING LEVEL OF NONSPECIFIC PROTEIN BINDING BELOW 10 PERCENT; FOR ASSAY WITHOUT WASH STEP | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1999-07-06 | — | — | US | disclosed |
| US-5677196-A | BIODETECTOR COMPRISING THE SURFACE IMMOBILIZED CAPTURE MOLECULES WHICH WILL SELECTIVELY BINDING AN ANALYTE; SPECTROPHOTOMETERS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1997-10-14 | — | — | US | disclosed |
| US-4607109-A | Nitrogen containing compounds, their preparation and use of same for the preparation of decalin keton derivatives | FIRMENICH SA (CH) | 1986-08-19 | — | — | US | disclosed |
| US-4405589-A | ALKYL OR ARYL SILICON CHLORIDES, AMMONIA, ROASTING | UBE INDUSTRIES, LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4113680-A | Method for preparing 17 α-ester-21-halo pregnanes | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |