SCHEMBL52125

SCHEMBL52125

c1ccc([SiH2]c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
ACHE P22303 2/20 0.44
ALOX12 P18054 2/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 5/20 0.40
TDP1 Q9NUW8 4/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5702857 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Hydrochloric Acid SCHEMBL312008 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
SCHEMBL2793385 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Fluoride SCHEMBL704196 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
SCHEMBL3133054 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
SCHEMBL2793388 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Ammonia Solution, Strong SCHEMBL11868999 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Hydrochloric Acid SCHEMBL15122374 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Water SCHEMBL6913191 0.96 TSHR (0.41) TSHRACHEALOX12LMNAHSD17B10
Ethylene SCHEMBL29078356 0.93 TSHR (0.39) TSHRACHEALOX12LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14821 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12640364-B2 High capacity, long cycle life battery anode materials, compositions and methods DYNAMIC MATERIAL SYSTEMS LLC (US) 2026-05-26 US claimed
CN-122080087-A Pyridine-imine type metal complex and preparation method and application thereof 2026-05-26 CN claimed
CN-122079717-A Efficient oxygen deleting reagent and application thereof in carbon resource molecular skeleton deoxidizing reconstruction 2026-05-26 CN claimed
CN-117839758-B Spray-formed microsphere modified titanium silicalite molecular sieve catalyst, preparation method and application thereof in production of epoxybutane TIANJIN DAGU CHEMICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122011012-A (S) -tert-butyl ((2-methyl-7- (trimethylsilyl) hept-6-alkyne-1-yl) oxy) diphenyl silane and synthesis method and application thereof 山东省农业科学院 2026-05-12 CN claimed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
EP-4686724-A1 METHOD FOR THE DEUTERATION OF SILANES AND PINACOLBORANE Consejo Superior De Investigaciones Científicas (CSIC) (ES) 2026-02-04 EP claimed
US-20250388723-A1 SILYL ETHER-CONTAINING POLYMERS AND USES THEREOF ENTEGRIS INC (US) 2025-12-25 US claimed
WO-2025217341-A1 LOW TEMPERATURE TRICHLOROSILANE HYDROGENATION AGC CARBON INC. (US) 2025-10-16 WO claimed
US-20250313482-A1 LOW TEMPERATURE TRICHLOROSILANE HYDROGENATION AGC CARBON INC. (US) 2025-10-09 US claimed
US-4139403-A Dinitroalkyl and fluorodinitroalkyl silicon compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-02-13 US claimed
US-4115427-A BY REACTION OF A HYDROGEN SILANE AND AN AMINE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-09-19 US claimed
US-4110294-A POLYIMIDES CIBA-GEIGY CORPORATION (US) 1978-08-29 US claimed
US-4090981-A ALUMINOSILICATE ZEOLITE MOBILE OIL CORPORATION (US) 1978-05-23 US claimed
US-4089853-A Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline AMERICAN CYANAMID COMPANY (US) 1978-05-16 US claimed
US-4026827-A Preparation of high-molecular weight thermoplastic polyorganosilicic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-05-31 US claimed
US-4014816-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1977-03-29 US claimed
US-4006226-A Anticonvulsant diphenylsilanes DOW CORNING CORPORATION (US) 1977-02-01 US claimed
US-3993630-A Polyimide, polyamide-imide or polyamide-acids with olefin end groups in combination with a reactive Schiff base compound CIBA-GEIGY CORPORATION (US) 1976-11-23 US claimed
US-3939137-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1976-02-17 US claimed