Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221171 | 1.00 | DPP4 (0.37) | DPP4APPSLC7A5FFAR1AAK1 | |
| SCHEMBL6032244 | 0.89 | AAK1 (0.35) | DPP4APPSLC7A5AAK1 | |
| SCHEMBL6246072 | 0.83 | CYP2C19 (0.39) | AAK1 | |
| SCHEMBL3453796 | 0.82 | DPP4 (0.37) | DPP4APPSLC7A5FFAR1AAK1 | |
| SCHEMBL28937621 | 0.79 | FFAR1 (0.33) | DPP4FFAR1 | |
| SCHEMBL17513198 | 0.78 | FFAR1 (0.41) | APPFFAR1AAK1 | |
| SCHEMBL28284788 | 0.77 | DPP4 (0.41) | DPP4 | |
| SCHEMBL28032950 | 0.77 | DPP4 (0.41) | DPP4 | |
| SCHEMBL27773550 | 0.76 | GABBR2 (0.42) | DPP4SLC7A5AAK1 | |
| SCHEMBL28304220 | 0.73 | DPP4 (0.33) | DPP4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966940-B | A kind of preparation method of Sitagliptin phosphate intermediate N arylmethyl -2S- cyano methyl acridine | 新发药业有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-105294479-A | Preparation method of 3R-amino substituted butyrylamide derivative | XINFA PHARMACEUTICAL CO LTD | 2016-02-03 | — | — | CN | disclosed |