SCHEMBL28055265

SCHEMBL28055265

C[C@@H]1CN(OC(=O)C(C)(C)C)CCN1CCC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28058819 0.86 PARP1 (0.31)
SCHEMBL28058918 0.86 PARP1 (0.31)
SCHEMBL28058839 0.85 DRD3 (0.31)
SCHEMBL28058929 0.85 DRD3 (0.31)
SCHEMBL28776242 0.83 DRD3 (0.30)
SCHEMBL28289023 0.82 DRD3 (0.37)
SCHEMBL28055328 0.81 SIGMAR1 (0.39)
SCHEMBL27742729 0.81 SCN1A (0.30)
SCHEMBL27721977 0.81 SCN1A (0.30)
SCHEMBL27722011 0.81 SCN1A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294655-B The compound and application thereof of CDK type small molecular inhibitor 广东东阳光药业有限公司 2019-03-15 CN disclosed
CN-105294655-A CDK small-molecule inhibitor compounds and application therefore GUANGDONG HEC PHARMACEUTICAL 2016-02-03 CN disclosed