SCHEMBL28055368

SCHEMBL28055368

O=C(O)c1ccc(-c2ccc3cc(C(=O)O)cnc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.60
PDGFRB P09619 1/20 0.54
PDGFRA P16234 1/20 0.54
NR1H4 Q96RI1 1/20 0.45
MKNK1 Q9BUB5 2/20 0.44
MKNK2 Q9HBH9 2/20 0.44
ESR2 Q92731 1/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RXRA P19793 2/20 0.43
RXRB P28702 2/20 0.43
MAP4K4 O95819 1/20 0.43
RARA P10276 1/20 0.43
RARB P10826 1/20 0.43
RARG P13631 1/20 0.43
HPGDS O60760 1/20 0.43
BCL2L1 Q07817 1/20 0.43
BAD Q92934 1/20 0.43
P4HA1 P13674 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69368 0.86 MGAM (0.68) MGAMPDGFRBPDGFRAKDM4EHSD17B10
SCHEMBL27701668 0.80 MGAM (0.60) MGAMPDGFRBPDGFRAHSD17B10HPGDS
SCHEMBL9939727 0.80 ESR2 (0.73) MGAMPDGFRBPDGFRAESR2MAP4K4
SCHEMBL1353291 0.79 MGAM (0.64) MGAMPDGFRBPDGFRAESR2HPGDS
Hydrochloric Acid SCHEMBL8891443 0.79 PDGFRB (0.53) PDGFRBPDGFRAMKNK2ESR2RXRA
SCHEMBL4398475 0.79 MGAM (0.68) MGAMPDGFRBPDGFRAMKNK2KDM4E
SCHEMBL5757744 0.78 MGAM (0.54) MGAMPDGFRBPDGFRAKDM4EHPGDS
SCHEMBL4158038 0.78 MGAM (0.62) MGAMPDGFRBPDGFRAMAP4K4HPGDS
SCHEMBL21063895 0.78 MGAM (0.62) MGAMPDGFRBPDGFRAESR2HSD17B10
SCHEMBL29373133 0.78 MGAM (0.62) MGAMPDGFRBPDGFRAHPGDSP4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105419785-A Subject and object compounded multi-photon polarization laser material based on metal-organic framework and preparation method of subject and object compounded multi-photon polarization laser material UNIV ZHEJIANG 2016-03-23 CN disclosed