SCHEMBL69368

SCHEMBL69368

O=C(O)c1cnc2cc(C(=O)O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.68
TDP1 Q9NUW8 2/20 0.50
P4HA1 P13674 3/20 0.48
P4HTM Q9NXG6 2/20 0.48
HPGDS O60760 3/20 0.47
MIF P14174 1/20 0.47
PSMD14 O00487 1/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27701668 0.90 MGAM (0.60) MGAMTDP1P4HA1P4HTMHPGDS
SCHEMBL10465639 0.86 MGAM (0.70) MGAMTDP1P4HA1P4HTMMIF
SCHEMBL28055368 0.86 MGAM (0.60) MGAMP4HA1P4HTMHPGDSPSMD14
SCHEMBL1353291 0.85 MGAM (0.64) MGAMP4HA1P4HTMHPGDSMIF
SCHEMBL21063895 0.84 MGAM (0.62) MGAMP4HA1P4HTMHPGDSMIF
SCHEMBL22672767 0.84 TDP1 (0.54) MGAMTDP1NPC1RAB9AKDM4E
SCHEMBL4158038 0.84 MGAM (0.62) MGAMP4HA1P4HTMHPGDSPSMD14
SCHEMBL20721962 0.84 CDH1 (0.50) MGAMTDP1NPC1RAB9AKDM4E
SCHEMBL20572273 0.84 MGAM (0.49) MGAMTDP1P4HA1P4HTMMIF
SCHEMBL6769263 0.84 MGAM (0.62) MGAMTDP1P4HA1P4HTMHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
CN-102405039-A Cosmetic or dermatological composition comprising a polymer containing linking groups, and cosmetic treatment method OREAL 2012-04-04 CN claimed
CN-102325518-A Cosmetic or pharmaceutical composition comprising a polycondensate, polycondensate and method of cosmetic treatment OREAL 2012-01-18 CN claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-105755480-B Efficient acidic cleaner 江苏筑磊电子科技有限公司 2018-06-19 CN disclosed
CN-105755480-A Efficient acidic cleaner 江苏筑磊电子科技有限公司 2016-07-13 CN disclosed
CN-102405039-B Comprise cosmetics or skin composition and cosmetic treatment method containing the polymer of connecting group 莱雅公司 2016-06-08 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
CN-102325518-A Cosmetic or pharmaceutical composition comprising a polycondensate, polycondensate and method of cosmetic treatment OREAL 2012-01-18 CN disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MGAM 1964/4885TDP1 3534/4885P4HA1 569/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 MGAM 1091/4885TDP1 3475/4885P4HA1 1018/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB MGAM 2758/4885TDP1 2239/4885P4HA1 2060/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA MGAM 2257/4885TDP1 3912/4885P4HA1 570/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA MGAM 3909/4885TDP1 2687/4885P4HA1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.