Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015355 | 0.96 | KMT2A (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL909706 | 0.94 | EPHX1 (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3956402 | 0.91 | MGAM (0.42) | MGAMGAASIMGAM2EPHX2 | |
| SCHEMBL3631878 | 0.85 | — | — | |
| SCHEMBL2555598 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL24364734 | 0.82 | EPHX1 (0.46) | EPHX2KMT2AEPHX1HPGD | |
| SCHEMBL868953 | 0.80 | BRD4 (0.47) | ALDH1A1L3MBTL1EPHX2KMT2AEPHX1 | |
| SCHEMBL10584364 | 0.80 | EPHX1 (0.44) | L3MBTL1EPHX2KMT2AEPHX1HPGD | |
| SCHEMBL12561124 | 0.80 | ALDH1A1 (0.43) | ALDH1A1EPHX2KMT2AHPGDTSHR | |
| SCHEMBL12561079 | 0.80 | SCN9A (0.34) | MGAMGAASIMGAM2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292130-B | A kind of synthetic method of EBP520 intermediate 2-hydroxyl-3-amino-4-cyclobutyl butanamide hydrochloride | SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-104292130-B | A kind of synthetic method of EBP520 intermediate 2-hydroxyl-3-amino-4-cyclobutyl butanamide hydrochloride | SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |