Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015355 | 0.98 | KMT2A (0.42) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL28055530 | 0.94 | MGAM (0.39) | EPHX1HPGDKMT2AEPHX2ALDH1A1 | |
| SCHEMBL3956402 | 0.90 | MGAM (0.42) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL10584364 | 0.86 | EPHX1 (0.44) | EPHX1HPGDKMT2AEPHX2POLB | |
| SCHEMBL8099254 | 0.85 | KMT2A (0.50) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL106265 | 0.85 | KMT2A (0.50) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL14606391 | 0.85 | KMT2A (0.50) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL18322599 | 0.85 | KMT2A (0.50) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| SCHEMBL3656797 | 0.85 | TSHR (0.48) | EPHX1HPGDKMT2AEPHX2KDM4E | |
| Hydrochloric Acid SCHEMBL27692491 | 0.83 | KMT2A (0.48) | EPHX1HPGDKMT2AEPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194671-A | Process for the preparation of β-ketocarboxylic acid esters | WACKER-CHEMIE GMBH (DE) | 1993-03-16 | — | — | US | claimed |
| US-9579528-B2 | Ketones as perfuming ingredients | FIRMENICH SA (CH) | 2017-02-28 | — | — | US | disclosed |
| US-8841488-B2 | Ketones as perfuming ingredients | FIRMENICH SA (CH) | 2014-09-23 | — | — | US | disclosed |
| US-20140030204-A1 | KETONES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2014-01-30 | — | — | US | disclosed |
| CN-102007204-B | Ketones as perfuming ingredients | FIRMENICH & CIE | 2013-01-23 | — | — | CN | disclosed |
| EP-2268779-B1 | KETONES AS PERFUMING INGREDIENTS | FIRMENICH & CIE (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-8329726-B2 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC. (CA) | 2012-12-11 | — | — | US | disclosed |
| US-20120083482-A1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC. | 2012-04-05 | — | — | US | disclosed |
| CN-102007204-A | Ketones as perfuming ingredients | FIRMENICH & CIE | 2011-04-06 | — | — | CN | disclosed |
| US-20110014143-A1 | KETONES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2011-01-20 | — | — | US | disclosed |
| EP-2268779-A1 | KETONES AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009128026-A1 | KETONES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2009-10-22 | — | — | WO | disclosed |
| US-6972304-B2 | Aqueous ink compositions | XEROX CORPORATION (US) | 2005-12-06 | — | — | US | disclosed |
| US-6906118-B2 | Phase change ink compositions | XEROX CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-20030105185-A1 | Phase change ink compositions | XEROX CORPORATION | 2003-06-05 | — | — | US | disclosed |
| US-20030079644-A1 | Aqueous ink compositions | XEROX CORPORATION | 2003-05-01 | — | — | US | disclosed |
| US-5198322-A | Positively operating radiation-sensitive mixture containing a polyfunctional α-diazo-β-keto ester and radiation-sensitive recording material containing this mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-30 | — | — | US | disclosed |
| US-5194671-A | Process for the preparation of β-ketocarboxylic acid esters | WACKER-CHEMIE GMBH (DE) | 1993-03-16 | — | — | US | disclosed |
| US-4996301-A | Polyfunctional α-diazo-β-keto esters and their use in light-sensitive compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083482-A1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | HGF, MET, KDR | EPHX1 1955/4885HPGD 680/4885KMT2A 2894/4885 |
| US-20140030204-A1 | KETONES AS PERFUMING INGREDIENTS | C5, CBR3, C9 | EPHX1 2107/4885HPGD 2163/4885KMT2A 1237/4885 |
| US-20110014143-A1 | KETONES AS PERFUMING INGREDIENTS | CBR3, CBR1, C5 | EPHX1 447/4885HPGD 719/4885KMT2A 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.