Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070319 | 0.92 | DPP4 (0.58) | KMT2AFOLH1DPP4BCL2BCL2L1 | |
| SCHEMBL340250 | 0.92 | DPP4 (0.58) | KMT2AFOLH1DPP4BCL2BCL2L1 | |
| Hydrogen Sulfide SCHEMBL27779487 | 0.90 | DPP4 (0.56) | KMT2AFOLH1DPP4PTPN1BCL2 | |
| Phenol SCHEMBL27575460 | 0.86 | KEAP1 (0.50) | KMT2AFOLH1DPP4PTPN1BCL2 | |
| SCHEMBL29484232 | 0.83 | DPP4 (0.54) | KMT2AFOLH1DPP4FFAR1FFAR4 | |
| SCHEMBL29484236 | 0.83 | DPP4 (0.54) | KMT2AFOLH1DPP4FFAR1FFAR4 | |
| SCHEMBL28825976 | 0.83 | DPP4 (0.48) | KMT2AFOLH1DPP4PTPN1BCL2 | |
| SCHEMBL9474651 | 0.83 | LMNA (0.64) | KMT2AFOLH1PTGER1PTGER4PTGER3 | |
| SCHEMBL9474898 | 0.83 | LMNA (0.64) | KMT2AFOLH1FFAR1FFAR4L3MBTL1 | |
| SCHEMBL14720214 | 0.83 | PLA2G10 (0.64) | KMT2AFOLH1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324879-B | The carbonate products containing xenyl used in nonaqueous electrolytic solution, the electric energy storage device for having used the nonaqueous electrolytic solution and the nonaqueous electrolytic solution | 宇部兴产株式会社 | 2018-07-27 | — | — | CN | claimed |
| CN-105324879-A | Nonaqueous electrolyte solution, electricity storage device using same, and biphenyl group-containing carbonate compound used in same | UBE INDUSTRIES | 2016-02-10 | — | — | CN | claimed |
| CN-105324879-B | The carbonate products containing xenyl used in nonaqueous electrolytic solution, the electric energy storage device for having used the nonaqueous electrolytic solution and the nonaqueous electrolytic solution | 宇部兴产株式会社 | 2018-07-27 | — | — | CN | disclosed |
| CN-105324879-A | Nonaqueous electrolyte solution, electricity storage device using same, and biphenyl group-containing carbonate compound used in same | UBE INDUSTRIES | 2016-02-10 | — | — | CN | disclosed |