Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL27678273 | 1.00 | GPR84 (0.42) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL28281210 | 1.00 | GPR84 (0.42) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL27678274 | 1.00 | GPR84 (0.42) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL27678270 | 1.00 | GPR84 (0.42) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL28282568 | 0.98 | GPR84 (0.40) | GPR84FFAR1ACE2MAPTLCK | |
| L-Lactic Acid SCHEMBL30241866 | 0.94 | CA2 (0.38) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL27658143 | 0.94 | CA2 (0.38) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL29042837 | 0.92 | CA2 (0.37) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL29043106 | 0.92 | CA2 (0.37) | GPR84FFAR1ACE2MAPTLCK | |
| Lactic Acid SCHEMBL29042836 | 0.92 | CA2 (0.37) | GPR84FFAR1ACE2MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418575-B | A method of natural VE is extracted using two step stripping process | 华东理工大学 | 2019-03-29 | — | — | CN | claimed |
| CN-105418575-A | Method for extracting natural vitamin E through two-step reextraction method | UNIV EAST CHINA SCIENCE & TECH | 2016-03-23 | — | — | CN | claimed |
| CN-105418575-A | Method for extracting natural vitamin E through two-step reextraction method | UNIV EAST CHINA SCIENCE & TECH | 2016-03-23 | — | — | CN | disclosed |