Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055879 | 0.67 | NPC1 (0.42) | MAPK1ALDH1A1HTR2CHTR2BHTR2A | |
| SCHEMBL6762451 | 0.67 | ALDH1A1 (0.36) | MAPK1ALDH1A1HTR2BCYP1A2LMNA | |
| SCHEMBL7177921 | 0.66 | KDM1A (0.48) | MAPK1ALDH1A1KDM1AHTR2CHTR2B | |
| SCHEMBL31295703 | 0.65 | ALDH1A1 (0.67) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL358976 | 0.65 | ALDH1A1 (0.67) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7519287 | 0.63 | ALDH1A1 (0.63) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31465796 | 0.63 | ALDH1A1 (0.63) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9122691 | 0.61 | KDM1A (0.40) | MAPK1ALDH1A1KDM1AHTR2CHTR2B | |
| SCHEMBL11807332 | 0.61 | KMT2A (0.53) | MAPK1ALDH1A1KDM1AHTR2CHTR2B | |
| Bromide SCHEMBL6343983 | 0.61 | ALDH1A1 (0.60) | MAPK1ALDH1A1GAAPBRM1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012098-B | Derivative of fluorenes and preparation method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | claimed |
| CN-103012098-B | Derivative of fluorenes and preparation method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | disclosed |