Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762451 | 0.83 | ALDH1A1 (0.36) | MAPK1ALDH1A1PTPRCCYP1A2TP53 | |
| SCHEMBL18926276 | 0.72 | NPC1 (0.55) | NPC1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL7520996 | 0.69 | KMT2A (0.61) | NPC1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL14804285 | 0.69 | MEN1 (0.50) | NPC1MEN1KMT2AGAAMAPK1 | |
| Benzene SCHEMBL28134446 | 0.67 | MEN1 (0.59) | NPC1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL28055941 | 0.67 | MAPK1 (0.39) | MEN1KMT2AGAAMAPK1ALDH1A1 | |
| SCHEMBL28219801 | 0.67 | AURKA (0.32) | MAPK1ALDH1A1PTPRC | |
| SCHEMBL19125933 | 0.66 | ALDH1A1 (0.63) | NPC1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL7522172 | 0.66 | ALDH1A1 (0.63) | NPC1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL28849090 | 0.63 | ALDH1A1 (0.38) | MAPK1ALDH1A1PTPRCCYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012098-B | Derivative of fluorenes and preparation method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | claimed |
| CN-103012098-B | Derivative of fluorenes and preparation method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | disclosed |