Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156398 | 0.95 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| Phosphine SCHEMBL28031041 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27991089 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28106994 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| Water SCHEMBL28060834 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| Propanol SCHEMBL28326995 | 0.91 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Ethylamine SCHEMBL28056822 | 0.89 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28275235 | 0.88 | — | — | |
| SCHEMBL28699233 | 0.87 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Diethylamine SCHEMBL28121345 | 0.87 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105733197-A | Heat-conducting flame-retardant epoxy resin and preparation method thereof | 惠州学院 | 2016-07-06 | — | — | CN | disclosed |