Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062313 | 0.88 | KCNJ1 (0.43) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL1644779 | 0.82 | HSD17B10 (0.49) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL3978869 | 0.82 | ALDH1A1 (0.46) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL4265596 | 0.82 | ALDH1A1 (0.49) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL1127509 | 0.79 | KCNJ1 (0.43) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL31463506 | 0.79 | KCNJ1 (0.43) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL8689842 | 0.79 | HSD17B10 (0.49) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL3888275 | 0.79 | ALDH1A1 (0.49) | PTPRCS100A4KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL7741732 | 0.77 | PTPRC (0.63) | PTPRCS100A4ALDH1A1MAPTTDP1 | |
| SCHEMBL984873 | 0.74 | KCNJ1 (0.67) | KCNJ1KCNH2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392788-A | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC | 2016-03-09 | — | — | CN | disclosed |