SCHEMBL28056101

SCHEMBL28056101

O=P(O)(O)[CH]c1ccccc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.50
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
ERN1 O75460 1/20 0.41
MAOB P27338 1/20 0.40
IKBKB O14920 1/20 0.39
RAF1 P04049 1/20 0.39
RPS6KB1 P23443 1/20 0.39
MAPK1 P28482 1/20 0.39
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
KDR P35968 1/20 0.39
PRKAG1 P54619 1/20 0.39
MAP2K1 Q02750 1/20 0.39
PRKAA1 Q13131 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779745 0.72 NFE2L2 (0.54) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL779504 0.70 CES2 (0.42) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL779472 0.70 NFE2L2 (0.50) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL779505 0.70 CES2 (0.42) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL127515 0.69
SCHEMBL20465749 0.69
SCHEMBL87096 0.69
SCHEMBL208739 0.69
SCHEMBL30039913 0.69
SCHEMBL29540911 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103259044-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2016-02-10 CN disclosed