SCHEMBL28056107

SCHEMBL28056107

CC1CCC2C(CCC(C)C2C(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPP5C P53041 1/20 0.38
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PMP22 Q01453 1/20 0.33
TFPI2 P48307 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
GRM2 Q14416 1/20 0.32
GRM3 Q14832 1/20 0.32
POLB P06746 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
KMT2A Q03164 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CA P62136 1/20 0.30
PPP1CC P36873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28056019 0.87 PPP5C (0.39) PPP5CLMNAKDM4EGMNNPMP22
SCHEMBL20854025 0.77 POLB (0.38) PPP5CLMNAKDM4EGMNNPMP22
SCHEMBL24731769 0.75 L3MBTL1 (0.31)
SCHEMBL12949885 0.74 PPP5C (0.38) PPP5CLMNAKDM4EGMNNPMP22
SCHEMBL3984067 0.74 POLB (0.37) PPP5CLMNAKDM4EGMNNPMP22
SCHEMBL34468414 0.74 POLB (0.37) PPP5CLMNAKDM4EGMNNPMP22
SCHEMBL11067015 0.72 L3MBTL1 (0.35)
SCHEMBL11067021 0.72 L3MBTL1 (0.35)
SCHEMBL11067012 0.72 L3MBTL1 (0.35)
SCHEMBL1196210 0.72 LMNA (0.50) PPP5CLMNAKDM4EGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392818-A Highly heat-resistant and highly transparent polycarbonate ester, and preparation method therefor SK CHEMICALS CO LTD 2016-03-09 CN claimed
CN-107108870-A Prepare the new method of the makrolon with the high grade of transparency and high-fire resistance SK化学公司 2017-08-29 CN disclosed
CN-105392818-A Highly heat-resistant and highly transparent polycarbonate ester, and preparation method therefor SK CHEMICALS CO LTD 2016-03-09 CN disclosed