SCHEMBL28056150

SCHEMBL28056150

CO[PH](=O)c1ccc(F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
NFE2L2 Q16236 2/20 0.34
ALDH1A1 P00352 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
ATM Q13315 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191791 0.85
SCHEMBL258150 0.85
SCHEMBL190026 0.85
SCHEMBL11512701 0.78 ACHE (0.40) ACHEALDH1A1CES2CES1CA1
SCHEMBL914550 0.76 CA12 (0.41) ACHEALDH1A1NPC1RAB9AMEN1
SCHEMBL12713096 0.76 MAPT (0.36) ACHEALDH1A1MEN1MAPTKMT2A
SCHEMBL258394 0.75 CA4 (0.38) ACHEALDH1A1RAB9AMAPTMAPK1
SCHEMBL11805329 0.74 ACHE (0.40) ACHENFE2L2ALDH1A1NPC1RAB9A
SCHEMBL258292 0.73 CA4 (0.36) ALDH1A1RAB9AMAPTKMT2ACES2
SCHEMBL258618 0.73 CA4 (0.36) ALDH1A1RAB9AMAPTKMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103259044-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2016-02-10 CN disclosed