Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044949 | 0.85 | ALDH1A1 (0.39) | MPLALDH1A1KDM4EMAPTGAA | |
| SCHEMBL28785709 | 0.81 | ALDH1A1 (0.52) | MPLMMP2ALDH1A1TDP1KDM4E | |
| SCHEMBL2848722 | 0.79 | MPL (0.41) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL112134 | 0.79 | ALDH1A1 (0.50) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL29893374 | 0.79 | ALDH1A1 (0.50) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL12480337 | 0.78 | MPL (0.51) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL4218979 | 0.78 | ALB (0.39) | MPLKDM4EGAARXRARXRB | |
| Hydrochloric Acid SCHEMBL27585317 | 0.77 | ALDH1A1 (0.48) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| Hydrochloric Acid SCHEMBL4379610 | 0.77 | ALDH1A1 (0.48) | MPLALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL565066 | 0.76 | MMP2 (0.45) | MMP2ALDH1A1ADRA2BPTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114358-A | Novel compound and pharmacologically acceptable salt thereof | 明治制果药业株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |