Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287367 | 0.88 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL3793915 | 0.85 | KDM4E (0.56) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL6976150 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10MAPTGAA | |
| SCHEMBL6981561 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10MAPTGAA | |
| SCHEMBL3543838 | 0.84 | GAA (0.58) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL22895657 | 0.84 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL6977523 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10MAPTGAA | |
| SCHEMBL6971942 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL17287387 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL1397384 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4EHSD17B10POLBHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003278-B | Arylamino purine derivatives, preparation method and medical application thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) Co.,Ltd. (CN) | 2016-03-30 | — | — | CN | disclosed |