Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL1831068 | 0.88 | TSHR (0.44) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL165694 | 0.87 | ALDH1A1 (0.43) | CA1CA2CA7CA13ALDH1A1 | |
| Diaminooctane SCHEMBL31657030 | 0.86 | APP (0.46) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL10611732 | 0.86 | APP (0.46) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL31657029 | 0.86 | APP (0.46) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL31656983 | 0.86 | APP (0.46) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8184072 | 0.86 | EPHX1 (0.39) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL27888163 | 0.85 | CA1 (0.40) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL12506224 | 0.85 | CA1 (0.40) | BLMLMNASLC6A6CYP2C19CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL17385554 | 0.84 | LMNA (0.70) | BLMLMNASLC6A6CYP2C19CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111099834-A | Preparation method of efficient heat-conducting composite graphene oxide film | 南京新月材料科技有限公司 | 2020-05-05 | — | — | CN | claimed |
| CN-110591660-A | Preparation method of efficient heat-conducting composite graphene oxide film | 盐城增材科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-110560342-A | preparation method of efficient heat-conducting surface-modified graphene film | 盐城增材科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-111099834-A | Preparation method of efficient heat-conducting composite graphene oxide film | 南京新月材料科技有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-110591660-A | Preparation method of efficient heat-conducting composite graphene oxide film | 盐城增材科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110560342-A | preparation method of efficient heat-conducting surface-modified graphene film | 盐城增材科技有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-109354419-A | A kind of preparation method of high-efficiency heat conduction surface modified graphite alkene film | 南京新月材料科技有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-105502350-A | Graphene oxide and ionic liquid composite film and preparation method thereof | NANJING XINYUE MAT SCIENCE & TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |