Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | RRM2 | P31350 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955308 | 0.80 | GRM4 (0.56) | GRM4ALDH1A1 | |
| SCHEMBL28056510 | 0.78 | RRM2 (0.37) | RRM2 | |
| SCHEMBL7459419 | 0.74 | MEN1 (0.38) | RRM2ALDH1A1 | |
| SCHEMBL7246171 | 0.69 | — | — | |
| SCHEMBL1703801 | 0.68 | — | — | |
| SCHEMBL3395853 | 0.68 | CYP1A2 (0.40) | GRM4ALDH1A1 | |
| SCHEMBL4716502 | 0.68 | — | — | |
| SCHEMBL33992 | 0.67 | — | — | |
| SCHEMBL29382162 | 0.67 | — | — | |
| SCHEMBL27887980 | 0.67 | HRH4 (0.41) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432100-A | Synthesis method for 2-benzyloxy-5-aminopyrimidine-4-one serving as anticancer compound FU-O-G medicinal intermediate | 厦门市凯尔利信息科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105503740-A | Synthetic method for medicine intermediate 2-benzyloxy-5-aminopyrimidine-4-ketone of anticancer compound FU-O-G | CHENGDU QIESITE TECH CO LTD | 2016-04-20 | — | — | CN | claimed |
| CN-106432100-A | Synthesis method for 2-benzyloxy-5-aminopyrimidine-4-one serving as anticancer compound FU-O-G medicinal intermediate | 厦门市凯尔利信息科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105503740-A | Synthetic method for medicine intermediate 2-benzyloxy-5-aminopyrimidine-4-ketone of anticancer compound FU-O-G | CHENGDU QIESITE TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503740-A | Synthetic method for medicine intermediate 2-benzyloxy-5-aminopyrimidine-4-ketone of anticancer compound FU-O-G | CHENGDU QIESITE TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |