SCHEMBL28056510

SCHEMBL28056510

Nc1cnc(O)nc1C=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RRM2 P31350 1/20 0.37
FGFR4 P22455 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28056255 0.78 GRM4 (0.37) RRM2
SCHEMBL7459419 0.71 MEN1 (0.38) RRM2
SCHEMBL339177 0.70
SCHEMBL2201864 0.70
SCHEMBL28056515 0.69 PKM (0.37)
SCHEMBL28352277 0.67
SCHEMBL28056219 0.67 PIN1 (0.46)
SCHEMBL30009941 0.65 TRIM24 (0.33)
SCHEMBL1703801 0.65
SCHEMBL14940691 0.65 TRIM24 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106432102-A Synthetic method of anticancercompound FD-2 drug intermediate 2-N-butoxypolyethylene-5-amino pyrimidine-4-ketone 厦门市凯尔利信息科技有限公司 2017-02-22 CN claimed
CN-105541730-A Synthesis method for 2-n-butoxyl-5-aminopyrimidine-4-one as anticancer compound FD-2 drug intermediate CHENGDU QIESITE TECH CO LTD 2016-05-04 CN claimed
CN-106432102-A Synthetic method of anticancercompound FD-2 drug intermediate 2-N-butoxypolyethylene-5-amino pyrimidine-4-ketone 厦门市凯尔利信息科技有限公司 2017-02-22 CN disclosed
CN-105541730-A Synthesis method for 2-n-butoxyl-5-aminopyrimidine-4-one as anticancer compound FD-2 drug intermediate CHENGDU QIESITE TECH CO LTD 2016-05-04 CN disclosed