SCHEMBL28056458

SCHEMBL28056458

Fc1cc(CCl)cc(CCl)c1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.40
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL612513 0.94 IDO1 (0.46) IDO1CYP4F2CYP4A11CA12CA1
SCHEMBL2911886 0.91 IDO1 (0.44) IDO1CYP4F2CYP4A11CA12CA1
SCHEMBL25287039 0.89 IDO1 (0.34) IDO1
SCHEMBL31322887 0.84 DAO (0.38) IDO1
SCHEMBL14750162 0.84 DAO (0.38) IDO1
SCHEMBL1050358 0.83 CA1 (0.33) CA1
SCHEMBL16727024 0.82 ACHE (0.36) IDO1CYP4F2CYP4A11
SCHEMBL4059894 0.82 IDO1 (0.33) IDO1
SCHEMBL10969154 0.78 TSHR (0.32) IDO1
SCHEMBL23803913 0.78 IDO1 (0.31) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399632-A Synthetic method for 1,5-bis(chloromethyl)-3-fluorobenzene UNIV CHANGZHOU 2016-03-16 CN claimed
CN-105399632-A Synthetic method for 1,5-bis(chloromethyl)-3-fluorobenzene UNIV CHANGZHOU 2016-03-16 CN disclosed
CN-105399632-A Synthetic method for 1,5-bis(chloromethyl)-3-fluorobenzene UNIV CHANGZHOU 2016-03-16 CN disclosed
CN-105399632-A Synthetic method for 1,5-bis(chloromethyl)-3-fluorobenzene UNIV CHANGZHOU 2016-03-16 CN disclosed