SCHEMBL1050358

SCHEMBL1050358

ClCc1cc(CCl)cc(CCl)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19002944 0.89 TSHR (0.30) TSHR
SCHEMBL30539351 0.86 ACHE (0.50) CA1CA2TSHRACHE
SCHEMBL11743237 0.86 TSHR (0.44) TSHR
SCHEMBL11317816 0.86
SCHEMBL29482742 0.83
SCHEMBL29482741 0.83 TRPA1 (0.36) TSHR
SCHEMBL29482744 0.83
SCHEMBL608037 0.83 PTGS2 (0.39) TSHR
SCHEMBL17407558 0.83 IDO1 (0.39) TSHR
SCHEMBL18142147 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof HERCULES LLC (US) 2026-03-31 US claimed
EP-4192923-B1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2025-10-29 EP claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-116324124-B Hydrophobically modified associative thickener polymer and preparation method and application thereof 赫尔克里士有限公司 2025-03-18 CN claimed
CN-116324123-B Hydrophobically modified associative thickener polymer and preparation method and application thereof 赫尔克里士有限公司 2025-03-18 CN claimed
CN-115957595-B Method and separation system for removing ammonia in dry gas 中国石油化工股份有限公司 2025-03-04 CN claimed
CN-118995172-B Alkali-free betaine type oil displacement agent composition and preparation method thereof 北京银谷彩虹科技有限公司 2025-02-25 CN claimed
CN-119368019-A Acid and alkali resistant composite filter membrane and preparation method and application thereof 苏州仿生材料科学与工程中心 2025-01-28 CN claimed
CN-115957640-B Modified hollow fiber membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-01-03 CN claimed
CN-118995172-A Alkali-free betaine type oil displacement agent composition and preparation method thereof 北京银谷彩虹科技有限公司 2024-11-22 CN claimed
EP-4192923-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP claimed
EP-4192922-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP claimed
CN-115957595-A Method for removing ammonia in dry gas and separation system 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957640-A Modified hollow fiber membrane and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115572371-A Preparation method of ionic porous polymer material and application of essential oil in adsorption and terpene removal 杭州师范大学 2023-01-06 CN claimed
CN-111393822-B PC/ABS alloy plastic for shell material and preparation method thereof 佛山市汉纬新材料有限公司 2022-05-31 CN claimed
EP-3284772-B1 THIOETHERS, METHODS FOR THEIR PREPARATION, AND COMPOSITIONS INCLUDING SUCH THIOETHERS PRC DESOTO INT INC (US) 2019-09-11 EP claimed
EP-3284772-A1 THIOETHERS, METHODS FOR THEIR PREPARATION, AND COMPOSITIONS INCLUDING SUCH THIOETHERS PRC-DESOTO INTERNATIONAL, INC. (US) 2018-02-21 EP claimed
EP-0877766-B1 PREPARATION OF BRANCHED POLYMERS DOW CHEMICAL CO (US) 2001-11-28 EP claimed
US-5700887-A CONTACTING MONOMER WITH DIFUNCTIONAL ANIONIC INITIATOR TO FORM MACROMER, CONTACTING WITH MULTIFUNCTIONAL COUPLING AGENT, CONTACTING WITH TERMINATING AGENT THE DOW CHEMICAL COMPANY (US) 1997-12-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof PHOSPHO1, H1-10, H1-0 CA1 1492/4885CA2 2956/4885TSHR 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.