Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140895 | 0.95 | DPP4 (0.47) | DPP4PREPS1PR1S1PR3S1PR5 | |
| SCHEMBL28834183 | 0.93 | DPP4 (0.48) | DPP4S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL21986229 | 0.89 | DPP4 (0.43) | DPP4PREP | |
| SCHEMBL9660192 | 0.81 | S1PR1 (0.41) | DPP4S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15238182 | 0.80 | — | — | |
| SCHEMBL2605419 | 0.80 | — | — | |
| SCHEMBL5867154 | 0.79 | DPP4 (0.34) | DPP4PREP | |
| SCHEMBL15639189 | 0.79 | DPP4 (0.47) | DPP4PREP | |
| SCHEMBL2744920 | 0.77 | PREP (0.37) | DPP4PREP | |
| SCHEMBL499972 | 0.76 | S1PR1 (0.47) | DPP4S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294700-A | Preparation method for tert-butyl dioxy-3,8-diazabicyclo[3.2.1]octane-8-carboxylic acid | SHANGHAI SYNTHEALL PHARMACEUTICAL CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105294700-A | Preparation method for tert-butyl dioxy-3,8-diazabicyclo[3.2.1]octane-8-carboxylic acid | SHANGHAI SYNTHEALL PHARMACEUTICAL CO LTD | 2016-02-03 | — | — | CN | disclosed |