Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744920 | 0.85 | PREP (0.37) | DPP4PREPDPP8DPP9 | |
| SCHEMBL28834183 | 0.83 | DPP4 (0.48) | DPP4 | |
| SCHEMBL15639189 | 0.83 | DPP4 (0.47) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL5140895 | 0.81 | DPP4 (0.47) | DPP4PREP | |
| SCHEMBL28056504 | 0.79 | DPP4 (0.46) | DPP4PREP | |
| SCHEMBL21986229 | 0.74 | DPP4 (0.43) | DPP4PREPDPP8DPP9 | |
| SCHEMBL5867175 | 0.71 | DPP4 (0.34) | DPP4 | |
| SCHEMBL7409048 | 0.71 | DPP4 (0.53) | DPP4HRH3 | |
| SCHEMBL15238182 | 0.70 | — | — | |
| SCHEMBL2605419 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138416-B2 | Dipeptidyl peptidase inhibitors; heterocyclic amide and semicarbazide derivatives, e.g., (2-Cyano-1-(piperazine-2-yl)-carbonyl pyrrolidine bis-trifluoroacetate | TORRENT PHARMACEUTICALS LTD. (IN) | 2006-11-21 | — | — | US | claimed |
| EP-1492777-A1 | THIAZOLIDINE-4-CARBONITRILES AND ANALOGUES AND THEIR USE AS DIPEPTIDYL-PEPTIDASE INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2005-01-05 | — | — | EP | claimed |
| US-20040106802-A1 | Novel compounds and therapeutic uses thereof | TORRENT PHARMACEUTICALS LTD. | 2004-06-03 | — | — | US | claimed |
| US-20030225102-A1 | Novel compounds and therapeutic uses thereof | TORRENT PHARMACEUTICALS LTD. | 2003-12-04 | — | — | US | claimed |
| WO-2003084940-A1 | THIAZOLIDINE-4-CARBONITRILES AND ANALOGUES AND THEIR USE AS DIPEPTIDYL-PEPTIDAS INHIBITORS | SANKARANARAYANAN ALANGUDI (IN) | 2003-10-16 | — | — | WO | claimed |
| US-20040106802-A1 | Novel compounds and therapeutic uses thereof | TORRENT PHARMACEUTICALS LTD. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225102-A1 | Novel compounds and therapeutic uses thereof | GPR119, SLC5A1, SLC2A4 | DPP4 192/4885PREP 3803/4885HRH3 1489/4885 |
| US-20040106802-A1 | Novel compounds and therapeutic uses thereof | GPR119, SLC5A1, SLC2A3 | DPP4 146/4885PREP 3877/4885HRH3 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.